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KMID : 0616120120430030201
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Korean Journal of Pharmacognosy
2012 Volume.43 No. 3 p.201 ~ p.205
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Flavonoids Constituents of Duchesnea chrysantha
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Liu Qing
Ahn Jong-Hoon
Kim Seon-Beom
Hwang Bang-Yeon
Lee Mi-Kyeong
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Abstract
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In the course of screening pancreatic lipase inhibitory activity, total methanolic extract and EtOAc-soluble fraction of Duchesnea chrysantha showed significant inhibitory activity. Further fractionation and isolation of the EtOAc-soluble fraction resulted in five compounds, which were identified as trans-tiliroside (1), isovitexin (2), kaempferol-8-O--glucoside (3), kaempferol-3-O--glucoside (4) and quercetin-3-O--glucoside (5). All the five flavonoids derivatives were first reported from this plant but showed weak inhibitory effects on pancreatic lipase activity.
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KEYWORD
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Duchesnea chrysantha, Pancreatic lipase, Flavonoid, Trans-tiliroside, Obesity
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